DNLI Q4 Loss Narrower Than Expected, Hunter Syndrome Drug in Focus

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Denali Therapeutics (DNLI) reported a narrower-than-expected loss in Q4 2025, with a loss of 73 cents per share against an estimated 75 cents. The company is focused on the potential commercial launch of tividenofusp alfa for Hunter syndrome, with the FDA extending its review timeline to April 5, 2026. Denali also provided updates on other pipeline candidates, including DNL126 for Sanfilippo syndrome type A, and collaborations with Takeda, Biogen, and Sanofi.

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