Acknowledge suffering, refuse to indulge.

Treat the uncontrollable impermanence as a fact, and thus remain unmoved.
View setbacks as a process of growth and learning, therefore inevitable and beneficial.
In this way, everything is used for my benefit. Do not expect to gain anything, and thus give yourself the surplus.
The above teachings are called Stoicism in ancient Greece, and Zen Buddhism in East Asia. Obstacles are the way, and troubles are enlightenment.
Wisdom is a privilege, and also a form of solitude.